Techniques in Vascular & Interventional Radiology
Volume 10, Issue 1 , Pages 30-37, March 2007

Percutaneous Catheter Placement for Hepatic Arterial Infusion Chemotherapy

  • Yasuaki Arai, MD

      Affiliations

    • Division of Diagnostic Radiology, National Cancer Center, Tokyo, Japan.
    • Corresponding Author InformationAddress reprint requests to: Yasuaki Arai, MD, Chair, Division of Diagnostic Radiology, National Cancer Center, 5-1-1, Tsukiji, Chuo-ku, Tokyo, 104-0045, Japan.
    • ,
  • Yoshito Takeuchi, MD

      Affiliations

    • Division of Diagnostic Radiology, National Cancer Center, Tokyo, Japan.
    • ,
  • Yoshitaka Inaba, MD

      Affiliations

    • Department of Diagnostic and Interventional Radiology, Aichi Cancer Center, Nagoya, Japan.
    • ,
  • Hidekazu Yamaura, MD

      Affiliations

    • Department of Diagnostic and Interventional Radiology, Aichi Cancer Center, Nagoya, Japan.
    • ,
  • Yozo Sato, MD

      Affiliations

    • Department of Diagnostic and Interventional Radiology, Aichi Cancer Center, Nagoya, Japan.
    • ,
  • Takeshi Aramaki, MD

      Affiliations

    • Department of Imaging Diagnosis, Shizuoka Cancer Center, Shizuoka, Japan.
    • ,
  • Kiyoshi Matsueda, MD

      Affiliations

    • Department of Imaging Diagnosis, The Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan.
    • ,
  • Hiroshi Seki, MD

      Affiliations

    • Department of Radiology, Niigata Cancer Center, Niigata, Japan.

Hepatic arterial infusion chemotherapy employs a hepatic artery catheter as a conduit to achieve a high concentration of antineoplastic agents to liver tumors. Historically, this catheter placement has been performed via laparotomy. However, it may now be performed using less-invasive percutaneous image guided procedures. There are many anatomical hepatic arterial variations and complicated blood flow patterns. Various techniques are required to ensure high concentration of antineoplastic agents in liver tumors. These techniques are composed of arterial redistribution by embolization, percutaneous catheter placement applying “tip-fixation method,” and evaluation and management of flow patterns that reflect drug distribution. The role of interventional radiologists in hepatic arterial infusion chemotherapy is to create and manage the access to achieve these objectives.

Keywords: arterial infusion chemotherapy, arterial redistribution, tip-fixation, port system, drug distribution

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PII: S1089-2516(07)00071-6

doi:10.1053/j.tvir.2007.08.007

Techniques in Vascular & Interventional Radiology
Volume 10, Issue 1 , Pages 30-37, March 2007

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