Techniques in Vascular & Interventional Radiology
Volume 10, Issue 3 , Pages 207-220 , September 2007

Management of Hepatic Artery Steno-Occlusive Complications After Liver Transplantation

  • Wael E.A. Saad, MBBCh

      Affiliations

    • Corresponding Author InformationAddress reprint requests to: Wael E.A. Saad, MBBCh, Vascular Interventional Radiology Section, Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Ave, Box 648, Rochester, NY 14618.

References 

  1. Jain A, Costa G, Marsh W, et al. Thrombotic and nonthrombotic hepatic artery complications in adults and children following primary liver transplantation with long-term follow-up in 1000 consecutive patients. Transpl International. 2006;19:27–37
  2. Wozney P, Zajko AB, Bron KM, et al. Vascular complications after liver transplantation: a 5 year experience. AJR Am J Roentgenol. 1986;147:657–663
  3. Orons PD, Zajko AB, Bron KM, et al. Hepatic artery angioplasty after liver transplantation: experience in 21 allografts. J Vasc Interv Radiol. 1995;6:523–529
  4. Abad J, Hidalgo EG, Cantarero JM, et al. hepatic artery anastomotic stenosis after transplantation: treatment with percutaneous transluminal angioplasty. Radiology. 1989;171:661–662
  5. Castaneda F, Samuel KS, Hunter DW, et al. Reversible hepatic transplant ischemia: case report and review of the literature. Cardiovasc Interv Radiol. 1990;13:88–90
  6. Nemcek AA. Interventional radiology for transplantation: Arterial interventions. Proceedings of the Society of Interventional Radiology (SIR) 2003; Categorical Course J Vasc Interv Radiol. 2003;14(2pt 2 suppl):315–320
  7. Kodama Y, Sakuhara Y, Abo D, et al. Percutaneous transluminal angioplasty for hepatic artery stenosis after living donor liver transplantation. Liver Transpl. 2006;12:465–469
  8. Ueno T, Jones G, Martin A, et al. Clinical outcomes from hepatic artery stenting in liver transplantation. Liver Transpl. 2006;12:422–427
  9. Saad WEA, Davies MG, Sahler LG, et al. Hepatic artery stenosis in liver transplant recipients: primary treatment with percutaneous transluminal angioplasty. J Vasc Interv Radiol. 2005;16:795–805
  10. Saad WEA, Waldman DL. Endovascular repair of vascular lesions in solid organ transplantation. In:  Ouriel K,  Katzen BT,  Rosenfield K editor. Complications in Endovascular Therapy. New York, NY: Taylor and Francis Informa; 2006;p. 223–252
  11. Abassoglu O, Levy MF, Vodapally MS, et al. Hepatic artery stenosis after liver transplantation-incidence, presentation, treatment and long term outcome. Transplantation. 1997;63:250–255
  12. Langras AN, Marujo W, Stratta RJ, et al. Vascular complications after orthotopic liver transplantation. Am J Surg. 1991;161:76–83
  13. Marujo WC, Langras AN, Wood PR. Vascular complications following orthotopic liver transplantation: outcome and the role of urgent revascularization. Transplant Proc. 1991;23:1484–1486
  14. Tzakis AG, Gordon RD, Shaw BW, et al. Clinical preservation of hepatic artery thrombosis after liver transplantation in the cyclosporine era. Transplantation. 1985;40:667–671
  15. Blumhardt G, Ringe B, Lauchart W, et al. Vascular problems in liver transplantation. Transplant Proc. 1987;19:2412
  16. Zajko AB, Campbell WL, Logsdon GA, et al. Cholangiographic findings in hepatic artery occlusion after liver transplantation. AJR Am J Roentgenol. 1987;149:485–489
  17. Merion RM, Burtch GD, Ham JM, et al. The hepatic artery in liver transplantation. Transplantation. 1989;48:438–443
  18. Dodd GD, Memel DS, Zajko AB, et al. Hepatic artery stenosis and thrombosis in transplant recipients: Doppler diagnosis with resistive index and systolic acceleration time. Radiology. 1994;192:657–661
  19. Karatzas T, Lykaki-Karatzas M, Webb JN, et al. Vascular complications, treatment and outcome following orthotopic liver transplantation. Transplant Proc. 1997;29:2853–2855
  20. Mondragon Karani JB, Heaton ND, et al. The use of percutaneous transluminal angioplasty in hepatic artery stenosis after transplantation. Transplantation. 1994;57:228–231
  21. Segal MC, Zajko AB, Brower AD, et al. Hepatic artery thrombosis after liver transplantation: radiologic evaluation. AJR Am J Roentgenol. 1986;146:137–141
  22. Orons PD, Sheng R, Zajko AB. Hepatic artery stenosis in liver transplant recipients: prevalence and cholangiographic appearance of associated biliary complications. AJR Am J Roentgenol. 1995;165:1145–1149
  23. Raby N, Karoni J, Thomas S, et al. Stenoses of vascular anastomoses after hepatic transplantation: treatment with balloon angioplasty. AJR Am J Roentgenol. 1991;157:167–171
  24. Tzakis AG. The dearterialized liver graft. Semin Liver Dis. 1985;5:375–376
  25. Hesselink EJ, Slooff MJH, Schuur KH, et al. Consequences of hepatic artery pathology after orthotopic liver transplantation. Transplant Proc. 1987;19:2476–2477
  26. Denys AL, Qonadli SD, Durand F, et al. Feasibility and effectiveness of using coronary stents in the treatment of hepatic artery stenosis after orthotopic liver transplantation: preliminary report. AJR Am J Roentgenol. 2002;178:1175–1179
  27. Orons PD, Zajko AB, Bron KM, et al. Angiography and interventional procedures in liver transplantation. Radiol Clin North Am. 1995;33:541–558
  28. Uzochukwu LN, Bluth EI, Smetherman DH, et al. Early postoperative hepatic sonography as a predictor of vascular and biliary complications in adult orthotopic liver transplant patients. AJR Am J Roentgenol. 2005;185:1558–1570
  29. Marshall MM, Muiesan P, Srinivasan P, et al. Hepatic artery pseudoaneurysms following liver transplantation: Incidence, presenting features and management. Clin Radiol. 2001;56:579–587
  30. Stein M, Radich SM, Riegler JL, et al. Dissection of an iliac artery conduit to liver allograft: treatment with an endovascular stent. Liver Transpl Surg. 1999;5:252–254
  31. Cotroneo AR, DiStasi C, Cina A, et al. Stent placement in four patients with hepatic artery stenosis or thrombosis after liver transplantation. J Vasc Interv Radiol. 2002;13:619–623
  32. Narumi S, Osorio RW, Freise CE, et al. Hepatic artery pseudoaneurysm with hemobilia following angioplasty after liver transplantation. Clin Transplant. 1998;12:508–510
  33. Saad WEA, Davies MG, Saad NEA, et al. Trans-catheter thrombolysis of thrombosed hepatic arteries in liver transplant recipients: predictors of definitive endoluminal success and the role of pre-operative thrombolysis. Vasc Endovasc Surg. 2007;41:19–26
  34. Sheng R, Orons PD, Ramos HC, et al. Dissecting pseudoaneurysm of the hepatic artery: a delayed complication of angioplasty in a liver transplant. Cardiovasc Intervent Radiol. 1995;18:112–114
  35. Millonig G, Graziadei IW, Waldenberger P, et al. Percutaneous management of hepatic artery aneurysm: bleeding after liver transplantation. Cardiovasc Intervent Radiol. 2004;27:525–528
  36. Kim HJ, Kim KW, Kim AY, et al. Hepatic artery pseudoaneurysms in adult living-donor liver transplantation: efficacy of CT and Doppler sonography. AJR Am J Roentgenol. 2005;184:1549–1555
  37. Cheng TF, Chen YS, Huang TL, et al. Interventional radiologic procedures in liver transplantation. Transpl Int. 2001;14:223–229
  38. Figueras J, Busguets J, Dominguez J, et al. Intra-arterial thrombolysis in the treatment of acute hepatic artery thrombosis after liver transplantation. 1995;59:1356–1357
  39. Mazzaferro V, Esquivel CO, Mokowka L, et al. Factors responsible for hepatic artery thrombosis after pediatric liver transplantation. Tranplant Proc. 1989;21:2466–2467
  40. Esquivel CO, Koneru B, Karrer F, et al. Liver transplantation under one year of age. J Pediatr. 1987;110:545–548
  41. Mazzaferro V, Esquivel CO, Mokowka L, et al. Hepatic artery thrombosis after pediatric liver transplantation: medical or surgical event?. Tranplantation. 1989;4:971–977
  42. Yanaga K, Mokowka L, Shimida M, et al. Hepatic artery thrombosis following pediatric liver transplantation: assessment of blood flow measurement in allografts. Clin Transplant. 1989;3:184–189
  43. Parente D, Riou JY, Schmit P, et al. Variability of clinical presentation of hepatic artery thrombosis in pediatric liver transplantation: role of imaging modalities. Pediatr Radiol. 1990;20:253–257
  44. Hesselink EJ, Schilfguarde RV, Grond J, et al. Hepatic artery thrombosis after liver transplantation: clinical presentation and possible etiologic factors. Clin Transplant. 1988;2:306–311
  45. Bell R, Sheil AG, Thompson JF, et al. Vascular complications following orthotopic liver transplantation. Aust N Z J Surg. 1990;60:193–198
  46. D’Alessandro AM, Ploeg RJ, Knechtle H, et al. Re-transplantation of the liver: a seven year experience. Transplantation. 1993;55:1083–1089
  47. Drazar K, Shaked A, Liaik T, et al. Etiology and management of adult hepatic artery thrombosis after liver transplantation. Am Surg. 1996;62:237–240
  48. Berrocal T, Parron M, Alvarez-Luque A, et al. Pediatric liver transplantation: a pictoral essay of early of early and late complications. Radiographics. 2006;26:1187–1209
  49. Glockner JF, Forauer AR. Vascular or ischemic complications after liver transplantation. AJR Am J Roentgenol. 1999;173:1055–1059
  50. Nghiem HV, Tran K, Winter TC 3rd, et al: Imaging of complications in liver transplantation. Radiographics 16:825-840
  51. Vivarelli M, Cucchetti A, La Barba G, et al. Ischemic arterial complications after liver transplantation in the adult: multivariate analysis of risk factors. Arch Surg. 2004;139:1069–1074
  52. Samuel D, Gillet D, Castaing D, et al. Portal and arterial thrombosis in liver transplantation: a frequent event in severe rejection. Transplant Proc. 1989;21(1 pt 2):2225–2227
  53. Payen DM, Fratacci MD, Dupuy P, et al. Portal and hepatic arterial blood flow measurement of human transplanted liver by implanted Doppler probes: interest for early complications and nutrition. Surgery. 1990;107:417–427
  54. Mor E, Schwartz ME, Sheiner PA, et al. Prolonged preservation in University of Wisconsin solution associated with hepatic artery thrombosis after orthotopic liver transplantation. Transplantation. 1993;56:1399–1402
  55. Rogers J, Chavin KD, Kratz JM, et al. Use of autologous radial artery for revascularization of hepatic artery thrombosis after orthotopic liver transplantation: case report and review of indications and options for urgent hepatic artery reconstruction. Liver Transpl. 2001;7:913–917
  56. Bhattacharjya S, Gunson BK, Mirza DF, et al. Delayed hepatic artery thrombosis in adult orthotopic liver transplantation: a 12-year experience. Transplantation. 2001;71:1592–1596
  57. Sarfati PO, Boillot O, Baudin F, et al. Acute hepatic artery thrombosis in pediatric liver transplantation: surgical thrombectomy and in situ fibrinolysis. Ann Chir. 1992;46:605–609
  58. Katz E, Fukuzawa K, Schwartz M, et al. The splenic artery as the inflow in arterial revascularization of the liver graft in clinical liver transplantation. Transplantation. 1992;53:1373–1374
  59. Bjerkvik PS, Vatne K, Mathisen O, Soreide O. Percutaneous revascularization of postoperative hepatic artery thrombosis in a liver transplant. Transplantation. 1995;59:1746–1748
  60. Langnas AN, Marujo W, Stratta RJ, Wood RP, Shaw BW. Hepatic allograft rescue following arterial thrombosis: role of urgent revascularization. Transplantation. 1991;51:86–90
  61. Zajko AB, Brom KM, Starzl TE, et al. Angiography of liver transplantation patients. Radiology. 1985;157:305–311
  62. Rabkin JM, Orloff SL, Corless CL, et al. Hepatic allograft abscess with hepatic artery thrombosis. Am J Surg. 1998;175:354–359
  63. Vorwerk D, Gunther RW, Klever P, Riesener KP, Schumpelick V. Angioplasty and stent placement of treatment of hepatic artery thrombosis following liver transplantation. J Vasc Interv Radiol. 1994;5:309–311
  64. Hidalgo EG, Abad J, Cantarero JM, et al. High-dose intra-arterial urokinase for the treatment of hepatic artery thrombosis in liver transplantation. Hepatogastroenterology. 1989;36:529–532

PII: S1089-2516(07)00092-3

doi: 10.1053/j.tvir.2007.09.015

Techniques in Vascular & Interventional Radiology
Volume 10, Issue 3 , Pages 207-220 , September 2007