Techniques in Vascular & Interventional Radiology
Volume 10, Issue 4 , Pages 261-269, December 2007

Drug-Eluting Particles for Interventional Pharmacology

  • Eleni Liapi, MD

      Affiliations

    • The Russell H. Morgan Department of Radiology and Radiological Science, Division of Cardiovascular and Interventional Radiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
    • ,
  • Kwang-Hun Lee, MD

      Affiliations

    • The Russell H. Morgan Department of Radiology and Radiological Science, Division of Cardiovascular and Interventional Radiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
    • Division of Interventional Radiology, Department of Radiology and Research Institute of Radiological Science, Severance Hospital, Yonsei University College of Medicine, Seoul, Republic of Korea.
    • ,
  • Christos C. Georgiades, MD, PhD

      Affiliations

    • The Russell H. Morgan Department of Radiology and Radiological Science, Division of Cardiovascular and Interventional Radiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
    • ,
  • Kelvin Hong, MD

      Affiliations

    • The Russell H. Morgan Department of Radiology and Radiological Science, Division of Cardiovascular and Interventional Radiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
    • ,
  • Jean-Francois H. Geschwind, MD

      Affiliations

    • The Russell H. Morgan Department of Radiology and Radiological Science, Division of Cardiovascular and Interventional Radiology, The Johns Hopkins Hospital, Baltimore, MD, USA.
    • Corresponding Author InformationAddress reprint requests to: Jean-Francois H. Geschwind, MD, Interventional Radiology Research, The Johns Hopkins Hospital, Baltimore, MD 21287.

Chemoembolization with drug-eluting particles has been recently introduced in the field of interventional oncology. In this review, we will describe the pharmacokinetic properties and efficacy of all commercially available or under investigation drug-eluting particles and discuss the potentials and future of this new form of transcatheter arterial therapy for liver cancer.

Keywords: chemoembolization, hepatocellular carcinoma, hepatic metastasis, drug-eluting particles, doxorubicin, irinotecan

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PII: S1089-2516(08)00004-8

doi:10.1053/j.tvir.2008.03.003

Techniques in Vascular & Interventional Radiology
Volume 10, Issue 4 , Pages 261-269, December 2007

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