Techniques in Vascular & Interventional Radiology
Volume 10, Issue 4 , Pages 248-256, December 2007

Microspheres and Nonspherical Particles for Embolization

  • A. Laurent, MD, PhD

      Affiliations

    • Assistance Publique, Hôpitaux de Paris, Hôpital Lariboisière, Department of Interventional Neuroradiology, Paris, France.
    • Assistance Publique Hôpitaux de Paris and Institut National de la Recherche Agronomique, Center for Research of Interventional Imaging (CR2i), Jouy en Josas France.
    • University of Paris, Laboratoire Matières et Systèmes Complexes, UMR CNRS 7057, Paris, France.
    • Corresponding Author InformationAddress reprint requests to: Dr. A. Laurent, Department of Interventional Neuroradiology, Hôpital Lariboisière, 2 rue Ambroise Paré, 75475 Paris Cedex 10, France.

Last years, calibrated microspheres have proven their superiority in targeting embolization over non spherical particles in many applications. For the very near future they represent the best tool for controlling drug delivery in chemoembolization, under the two conditions that they would be image detectable and that the “dosimetry” would be tailored to pathological process.

Keywords: embolization, chemoembolization, particles, arterial occlusion, drug delivery, local delivery

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PII: S1089-2516(08)00011-5

doi:10.1053/j.tvir.2008.03.010

Techniques in Vascular & Interventional Radiology
Volume 10, Issue 4 , Pages 248-256, December 2007