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Genicular Artery Embolization Technique

  • Emily Sterbis
    Affiliations
    Department of Radiology, Division of Interventional Radiology, University of Colorado. Anschutz Medical Campus, Aurora, CO
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  • Leigh Casadaban
    Correspondence
    Address reprint requests to Leigh Casadaban, MD, MS, Department of Radiology, Division of Interventional Radiology, University of Colorado. Anschutz Medical Campus, 12401 E 17th Avenue, From the University of Colorado, Aurora, CO 80045.
    Affiliations
    Department of Radiology, Division of Interventional Radiology, University of Colorado. Anschutz Medical Campus, Aurora, CO
    Search for articles by this author
Published:December 21, 2022DOI:https://doi.org/10.1016/j.tvir.2022.100878
      Genicular artery embolization (GAE) is a safe and effective treatment for knee pain related to osteoarthritis, however there are several aspects of the procedure technique which may be unique. Familiarity with procedural steps, arterial anatomy, embolic endpoints, technical challenges, and potential complications is imperative for good clinical practice and outcomes. The success of GAE depends on correctly interpreting angiographic findings and variable anatomy, navigating small and acutely angled arteries, recognizing collateral supply, and avoiding non-target embolization. The procedure can potentially be performed for a wide range of patients with knee osteoarthritis. When effective, pain relief can be durable for many years. When done meticulously, adverse events from GAE are uncommon.

      Keywords

      Abbreviations:

      GAE (Genicular artery embolization), OA (Osteoarthritis), KL (Kellgren-Lawrence), VAS (Visual Analogue Scale), WOMAC (Western Ontario and McMaster University Osteoarthritis Index)
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      References

        • Okuno Y
        • Korchi AM
        • Shinjo T
        • et al.
        Transcatheter arterial embolization as a treatment for medial knee pain in patients with mild to moderate osteoarthritis.
        Cardiovasc Intervent Radiol. 2015; 38: 336-343
        • Okuno Y
        • Korchi AM
        • Shinjo T
        • et al.
        Midterm clinical outcomes and MR imaging changes after transcatheter arterial embolization as a treatment for mild to moderate radiographic knee osteoarthritis resistant to conservative treatment.
        J Vasc Interv Radiol. 2017; 28: 995-1002
        • Lee SH
        • Hwang JH
        • Kim DH
        • et al.
        Clinical outcomes of transcatheter arterial embolisation for chronic knee pain: mild-to-moderate versus severe knee osteoarthritis.
        Cardiovasc Intervent Radiol. 2019; 42: 1530-1536
        • Bagla S
        • Piechowiak R
        • Hartman T
        • et al.
        Genicular artery embolization for the treatment of knee pain secondary to osteoarthritis.
        J Vasc Interv Radiol. 2020; 31: 1096-1102
        • Landers S
        • Hely R
        • Page R
        • et al.
        Genicular artery embolization to improve pain and function in early-stage knee osteoarthritis-24-month pilot study results.
        J Vasc Interv Radiol. 2020; 31: 1453-1458
        • Little MW
        • Gibson M
        • Briggs J
        • et al.
        Genicular artEry embolizatioN in patiEnts with oSteoarthrItiS of the Knee (GENESIS) using permanent microspheres: interim analysis.
        Cardiovasc Intervent Radiol. 2021; 44: 931-940
        • Padia SA
        • Genshaft S
        • Blumstein G
        • et al.
        Genicular artery embolization for the treatment of symptomatic knee osteoarthritis.
        JB JS Open Access. 2021; 6
        • Bagla S
        • Piechowiak R
        • Sajan A
        • et al.
        Multicenter randomized sham controlled study of genicular artery embolization for knee pain secondary to osteoarthritis.
        J Vasc Interv Radiol. 2022; 33: 2-10 e2
        • Sanchez-Lopez E
        • Coras R
        • Torres A
        • et al.
        Synovial inflammation in osteoarthritis progression.
        Nat Rev Rheumatol. 2022; 18: 258-275
        • Mapp PI
        • Walsh DA:
        Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis.
        Nat Rev Rheumatol. 2012; 8: 390-398
        • Choi JW
        • Ro DH
        • Chae HD
        • et al.
        The value of preprocedural MR imaging in genicular artery embolization for patients with osteoarthritic knee pain.
        J Vasc Interv Radiol. 2020; 31: 2043-2050